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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
22.12
Human Site:
T422
Identified Species:
44.24
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
T422
S
R
S
F
F
D
P
T
S
Q
H
R
D
W
C
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
T422
S
R
G
F
F
D
P
T
S
Q
H
R
D
W
C
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
T422
S
R
S
F
F
D
P
T
S
Q
H
R
D
W
C
Dog
Lupus familis
XP_532428
589
65257
T509
S
R
S
C
F
D
P
T
S
Q
H
R
D
W
C
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
T421
P
R
S
F
F
D
P
T
S
Q
H
R
D
W
C
Rat
Rattus norvegicus
NP_001120765
501
55306
T421
P
R
S
F
F
D
P
T
S
Q
H
R
D
W
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
A482
P
R
S
V
F
D
P
A
S
Q
H
R
D
W
C
Chicken
Gallus gallus
XP_414975
484
53210
F404
D
T
S
P
R
S
F
F
D
P
S
S
Q
H
R
Frog
Xenopus laevis
Q6P7H4
477
53273
L397
P
R
S
C
F
D
P
L
S
Q
H
R
S
W
C
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
V410
H
R
N
M
F
D
P
V
A
Q
H
R
D
W
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
E221
T
T
N
E
D
E
S
E
P
T
A
K
R
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
T536
L
D
E
A
S
N
E
T
Q
P
E
T
G
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
80
6.6
73.3
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
80
6.6
73.3
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
75
% C
% Asp:
9
9
0
0
9
75
0
0
9
0
0
0
67
0
0
% D
% Glu:
0
0
9
9
0
9
9
9
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
42
75
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
75
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
9
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
0
9
0
0
75
0
9
17
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
9
75
0
0
9
0
0
% Q
% Arg:
0
75
0
0
9
0
0
0
0
0
0
75
9
0
9
% R
% Ser:
34
0
67
0
9
9
9
0
67
0
9
9
9
9
0
% S
% Thr:
9
17
0
0
0
0
0
59
0
9
0
9
0
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _